BIOTECH & AGRICULTURAL TECHNOLOGIES
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The researchers have developed cyclic peptide library that is applicable to phenotypic screening. The structure of each cyclic peptides is designed from genome information.
Grafting has been used historically to enhance yields or to increase tolerance against environmental stress and plant diseases.
The parasitic plant Striga Hermonthica causes damage to crops like corn, rice, and peas/beans in Africa, Asia, the USA and Africa.
Nagoya University researchers have invented an aqueous chemical reagent, termed ClearSee, that renders fixed plant tissues transparent to allow deep imaging by chemical screening. ClearSee rapidly diminishes chlorophyll autofluorescence while preserving the fluorescence of fluorescence proteins.
Nagoya University researchers have revealed that POEM (pollen tube-dependent ovule enlargement morphology) by mutation of gcs1 gene in Oryza sativa (rice) can allow the storage of a highly concentrated sucrose (98%) as a liquid.
Nagoya University researchers have succeeded in developing novel fluorescent compounds that allow users to overcome all current fluorescent dye problems. These novel compounds can be used to stain living cells well (< 500 MW) without any damage using low energy wavelength excitation (561 nm) and they are applicable to the two-photon excitation microscopy assay.
Researchers at Nagoya University have developed novel fluorescent dyes, based on a benzophosphole scaffold.
B-31 Novel synthetic auxin and its receptor that control gene expressions at specific part of the plant
Nagoya University researchers have succeeded in developing the auxin receptor (TIR1F79G) *by mutating an amino acid residue, and the novel synthetic auxin (27B) that specifically binds to TIR1F79G.
Researchers at Nagoya University prepared three patterns of promoters to express Cas9.
Nagoya University researchers have developed a continuous PM2.5 collection system from aerosol using a water film within the device. The water film is formed by a superhydrophilic surface and enables the collection of PM2.5 from gas phase.
Although it is known that ADAM family proteases cause the severe bleeding from haemorrhagic snake venom, the detailed mechanism of the haemorrhage is unclear. Researchers at Nagoya University have found that the target of ADAM proteases is a Wnt/β-catenin signal receptor, LRP5/6 which controls cell differentiation and proliferation.
Through random screening of a chemical library of over 20,000 compounds, Nagoya University researchers have succeeded in finding new compounds that can control stomatal opening in plants.
Nagoya University researchers have successfully elucidated functional molecular mechanism of the receptor tyrosine kinase-like orphan receptor 1 (ROR1) to develop molecular targeted drugs of lung adenocarcinoma.
The adult pi/ pi mouse is a mutant mouse that constantly exhibit generalized tonic- clonic seizures (GTCSs; alternatively, grand-mal seizures) for life (up to two years) without any epileptogenic induction.
Nagoya University researchers have succeeded in developing an Escherichia coli whole-cell biocatalyst for the direct hydroxylation of benzene into phenol. This in vivo method enables wild-type cytochrome P450BM3 (P450BM3) expressed in E.coli to activate and hydroxylate its non-native substrates, such as benzene.